Complex regulation of autophagy in cancer - integrated approaches to discover the networks that hold a double-edged sword.
第一作者:
János,Kubisch
第一单位:
Department of Genetics, Eötvös Loránd University, Pázmány P. s. 1C, H-1117 Budapest, Hungary.
作者:
关键词
AutophagyCancerERKFoxO1/3GSK3HIFIGFIRE1JNKMulti-target drug designNF-κBNRF2NetworkPKARASRegulationSREBPTFEBTGF-βTP53 tumor suppressor proteinWNTc-Jun N-terminal kinaseextracellular signal regulated protein kinaseforkhead family transcription factorglycogen synthase kinase-3hypoxia-inducible factorinositol-requiring protein 1insulin-like growth factornuclear factor erythroid 2-related factor 2nuclear factor kappa betap53protein kinase Asmall GTPase proteinsterol regulatory element-binding proteintranscription factor EBtransforming growth factor betawingless and int-like protein
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);自噬(Autophagy);疾病模型, 动物(Disease Models, Animal);人类(Humans);突变(Mutation);肿瘤(Neoplasms);信号传导(Signal Transduction)
DOI
10.1016/j.semcancer.2013.06.009
PMID
23810837
发布时间
2013-07-30
- 浏览36
Seminars in cancer biology
252-61页
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