换一批Therapeutic efficacy and molecular mechanisms of snake (Walterinnesia aegyptia) venom-loaded silica nanoparticles in the treatment of breast cancer- and prostate cancer-bearing experimental mouse models.
第一作者：
Gamal,Badr
第一单位：
Princess Al-Johara Al-Ibrahim Center for Cancer Research, Prostate Cancer Research Chair, College of Medicine, King Saud University, Riyadh, Saudi Arabia; Zoology Department, Faculty of Science, Assiut University, 71516 Assiut, Egypt. Electronic address: badr73@yahoo.com.
作者：
关键词
ApoptosisB-cell lymphoma 2B-cell lymphoma-extra largeBakBaxBcl-(XL)Bcl-2Bcl-2 family membersBcl-2 homologous antagonist/killerBcl-2-associated X proteinBcl-2-interacting mediator of cell deathBimCKCKRsCell signalingChemokinesMcl-1NPNanoparticlesPCaProliferationROSSnake venomWEVWEV+NPWalterinnesia aegyptia venomWalterinnesia aegyptia venom combined with nanoparticles.chemokinechemokine receptorsmyeloid cell leukemia sequence-1nanoparticlesprostate cancerreactive oxygen species
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);印迹法, 蛋白质(Blotting, Western);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);疾病模型, 动物(Disease Models, Animal);药物释放系统(Drug Delivery Systems);眼镜蛇科毒液类(Elapid Venoms);眼镜蛇科(Elapidae);女(雌)性(Female);男(雄)性(Male);乳房肿瘤, 实验性(Mammary Neoplasms, Experimental);小鼠(Mice);纳米共轭体(Nanoconjugates);前列腺肿瘤(Prostatic Neoplasms);二氧化硅(Silicon Dioxide);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1016/j.freeradbiomed.2013.06.018
PMID
23811005
发布时间
2022-03-30
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Free radical biology & medicine
175-189页
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