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关键词
9-cis retinoic acidAKTARCortDHTDMEMDMSODexDiabetesERαErkEstEstroneFBSGRGWGW501516IFNγIL-1βLXRαMAPKMRMifNRP4PICPPARδ/γPRPR elementsPR knockoutPR-KOPREPancreatic islet beta cellsPro-inflammatory cytokinesProgesterone receptorRARXRαRosiSC51089TNFαTOTO901317TRAF2androgen receptorcorticosteronedexamethasonedihydro-testosteronedimethyl sulfoxidedulbecco’s modified eagle’s mediumestrogen receptor αextracellular-signal-regulated kinase 1/2fetal bovine serumglucocorticoid receptorinterferon-γinterleukin-1βliver X receptorαmifepristonemineralocorticoid receptormitogen-activated protein kinasesnuclear receptorp53peroxisome proliferator-activated receptorδ/γpro-inflammatory cytokinesprogesteroneprogesterone receptorprotein 53protein kinase Bretinoid X receptor αrosiglitazonetumor necrosis factor receptor-associated factor 2tumor necrosis factor α
主题词
动物(Animals);细胞凋亡(Apoptosis);细胞存活(Cell Survival);细胞因子类(Cytokines);药物评价, 临床前(Drug Evaluation, Preclinical);基因敲低技术(Gene Knockdown Techniques);HEK293细胞(HEK293 Cells);人类(Humans);肼类(Hydrazines);降血糖药(Hypoglycemic Agents);炎症介导素类(Inflammation Mediators);胰岛素分泌细胞(Insulin-Secreting Cells);小鼠(Mice);氧氮杂|艹卓|类(Oxazepines);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);受体, 孕酮(Receptors, Progesterone);转录, 遗传(Transcription, Genetic)
DOI
10.1016/j.steroids.2013.06.005
PMID
23827354
发布时间
2013-08-21
- 浏览96
Steroids
987-95页
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