换一批
换一批Neu1 sialidase and matrix metalloproteinase-9 cross-talk regulates nucleic acid-induced endosomal TOLL-like receptor-7 and -9 activation, cellular signaling and pro-inflammatory responses.
作者：
关键词
2′-(4-methylumbelliferyl)-α-d-N-acetylneuraminic acid4MUNANA50 inhibitory concentrationG-protein coupled receptorGPCRGPCR Gα proteinsGPCR signalingIC(50)MMPMMP9Macrophage cellsNMBR receptorsNeu1 sialidaseSEAPTLRTLR signalingTOLL-like receptorsTamiflumatrix metalloproteinaseoseltamivir phosphatesecreted embryonic alkaline phosphatase
主题词
氨基喹啉类(Aminoquinolines);动物(Animals);细胞系(Cell Line);内颗粒(Endosomes);酶抑制剂(Enzyme Inhibitors);基因表达调控(Gene Expression Regulation);HEK293细胞(HEK293 Cells);人类(Humans);炎症(Inflammation);干扰素诱导剂(Interferon Inducers);巨噬细胞(Macrophages);基质金属蛋白酶9(Matrix Metalloproteinase 9);小鼠(Mice);NF-κB(NF-kappa B);神经氨酸酶(Neuraminidase);寡核苷酸类(Oligonucleotides);奥司他韦(Oseltamivir);RNA, 小分子干扰(RNA, Small Interfering);受体, 铃蟾肽(Receptors, Bombesin);信号传导(Signal Transduction);Toll样受体7(Toll-Like Receptor 7);Toll样受体9(Toll-Like Receptor 9)
DOI
10.1016/j.cellsig.2013.06.010
PMID
23827939
发布时间
2018-12-02
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Cellular signalling
2093-105页
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