BMP2 and GDF5 induce neuronal differentiation through a Smad dependant pathway in a model of human midbrain dopaminergic neurons.
作者:
关键词
BMP receptorBMP(s)BMP2BMPR(s)DADIVDorsomorphinGDF(s)GDF5GDNFMAPKMTTNNeuronal differentiationPBSRT-PCRSH-SY5Y cellsSmad 1/5/8Smad signallingSmad1, Smad5 and Smad8TGFVMbone morphogenetic protein receptor(s)bone morphogenetic protein(s)caBMPRIbconstitutively active BMPRIbday(s) in vitrodopaminergic/dopamineglial cell line-derived neurotrophic factorgrowth differentiation factor(s)mitogen activated protein kinasesnumber of repetitionsphosphate buffered salinereverse transcriptase-polymerase chain reactionthiazolyl blue tetrazolium bromidetransforming growth factorventral midbrain
主题词
骨形态发生蛋白质2(Bone Morphogenetic Protein 2);细胞系, 肿瘤(Cell Line, Tumor);生长分化因子5(Growth Differentiation Factor 5);人类(Humans);中脑(Mesencephalon);神经发生(Neurogenesis);重组蛋白质类(Recombinant Proteins);Smad蛋白质类(Smad Proteins)
DOI
10.1016/j.mcn.2013.06.006
PMID
23831389
发布时间
2013-10-04
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