换一批Presynaptic TRPV1 vanilloid receptor function is age- but not CB1 cannabinoid receptor-dependent in the rodent forebrain.
第一作者：
László,Köles
第一单位：
Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.
作者：
关键词
3Rs4-AP4-aminopyridine7-, 14-, 29- and 60-day-old7D, 14D, 29D, 60DACEAARCARRIVEAUCAmerican Radiolabeled ChemicalsAnimal Research: Reporting In Vivo ExperimentsBCABSACB(1) cannabinoid receptorCB(1)RDMSODPMDTTDopamineECFEDTAEGTAFRFederation for Laboratory Animal Science AssociationsFelasaGABAGlutamateHEPESKHRKOKrebs-HEPES-RingerLiGTPMAO BMgATPN-(2-hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)N-arachidonyl dopamineNADANOPMSFPVDFRTXSDSSEMSerotoninStriatumTBS-TTRPV(1) vanilloid receptorTRPV(1)R and TRPV(4)RTrisTris-buffered saline with Tween 20WTaCSFarachidonyl-2′-chloroethylamidearea-under-the-curveartificial cerebrospinal fluidbicinchoninic acidbovine serum albumincannabinoid receptor type 1dimethyl sulfoxidedisintegration per minutedithiothreitolenhanced chemi-fluorescenceethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acidethylenediaminetetraacetic acidfractional release knockoutlithium guanozine triphosphatemagnesium adenosine triphosphatemonoamine oxidase Bnitric oxidephenylmethanesulfonyl fluoridepolyvinylidene difluoridereplacement, reduction, refinementresiniferatoxinsEPSCssodium dodecyl sulfatespontaneous excitatory postsynaptic currentsstandard error of the meantransient release potential receptor vanilloid type 4tris(hydroxymethyl)aminomethanewild-typeγ-aminobutyric acid
主题词
动物(Animals);辣椒辣素(Capsaicin);纹状体(Corpus Striatum);多巴胺(Dopamine);兴奋性突触后电位(Excitatory Postsynaptic Potentials);女(雌)性(Female);谷氨酸(Glutamic Acid);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);突触前末梢(Presynaptic Terminals);放射性核素显像(Radionuclide Imaging);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, 大麻酚, CB1(Receptor, Cannabinoid, CB1);血清素(Serotonin);TRPV阳离子通道(TRPV Cation Channels)
DOI
10.1016/j.brainresbull.2013.06.007
PMID
23831917
发布时间
2018-12-02
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Brain research bulletin
126-35页
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