Receptor-mediated Ca2+ and PKC signaling triggers the loss of cortical PKA compartmentalization through the redistribution of gravin.
第一作者:
Micah B,Schott
第一单位:
Department of Basic Sciences, UND School of Medicine and Health Sciences, 501 N Columbia Rd., Grand Forks, ND 58202-9037, USA.
作者:
关键词
1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester)A-Kinase Anchoring ProteinAKAPAKAP12ATPBAPTA-AMBIMCB4CaMCalciumECFPEGFPEYFPG protein coupled receptorGPCRGravinIMInsP3PB1–3PDE4PKAPKCPLCPurinergic receptorRIISERCASESSOCESSeCKSSrc-Suppressed C-Kinase SubstrateTgWT[Ca(2+)](i)adenosine triphosphatebisindolylmaleimidecalcium–calmodulincalmodulin binding domain 4enhanced cyan fluorescent proteinenhanced green fluorescent proteinenhanced yellow fluorescent proteininositol triphosphateintracellular calcium concentrationionomycinphosphodiesterase type 4phospholipase Cpolybasic domains 1 through 3protein kinase Aprotein kinase Cregulatory subunit of type II PKAsarco/endoplasmic reticulum calcium ATPasestandard extracellular solutionstore-operated calcium entrythapsigarginwild-type/full-lengthβ2-adrenergic receptorβ2AR
医学主题词
A型激酶锚定蛋白质类(A Kinase Anchor Proteins);腺苷三磷酸(Adenosine Triphosphate);细菌蛋白质类(Bacterial Proteins);钙(Calcium);细胞周期蛋白质类(Cell Cycle Proteins);细胞系, 肿瘤(Cell Line, Tumor);细胞膜(Cell Membrane);环AMP依赖性蛋白激酶类(Cyclic AMP-Dependent Protein Kinases);胞质溶胶(Cytosol);酶抑制剂(Enzyme Inhibitors);基因表达调控(Gene Expression Regulation);基因, 报告(Genes, Reporter);绿色荧光蛋白质类(Green Fluorescent Proteins);人类(Humans);离子霉素(Ionomycin);发光蛋白质类(Luminescent Proteins);蛋白激酶C(Protein Kinase C);蛋白质结构, 三级(Protein Structure, Tertiary);蛋白质转运(Protein Transport);信号传导(Signal Transduction);毒胡萝卜内酯(Thapsigargin)
DOI
10.1016/j.cellsig.2013.07.004
PMID
23838009
发布时间
2021-10-21
- 浏览98
Cellular signalling
2125-35页
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