RNA-Seq Differentiates Tumour and Host mRNA Expression Changes Induced by Treatment of Human Tumour Xenografts with the VEGFR Tyrosine Kinase Inhibitor Cediranib.
第一作者:
James R,Bradford
第一单位:
Oncology, AstraZeneca Pharmaceuticals, Alderley Park, Cheshire, United Kingdom.
作者:
医学主题词
动物(Animals);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞周期(Cell Cycle);细胞低氧(Cell Hypoxia);细胞系, 肿瘤(Cell Line, Tumor);计算生物学(Computational Biology);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因调控网络(Gene Regulatory Networks);人类(Humans);肺肿瘤(Lung Neoplasms);小鼠(Mice);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);蛋白激酶抑制剂(Protein Kinase Inhibitors);喹唑啉类(Quinazolines);序列分析, RNA(Sequence Analysis, RNA);种特异性(Species Specificity);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1371/journal.pone.0066003
PMID
23840389
发布时间
2021-10-21
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