Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology.

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第一作者： Chao,Zhang

第一单位： Howard Hughes Medical Institute and Department of Cellular & Molecular Pharmacology, University of California, San Francisco , San Francisco, California 94158, United States.

作者： Chao,Zhang ^[1] ; Michael S,Lopez ; Arvin C,Dar ; Eva,Ladow ; Steven,Finkbeiner ; Cai-Hong,Yun ; Michael J,Eck ; Kevan M,Shokat

作者单位： Howard Hughes Medical Institute and Department of Cellular & Molecular Pharmacology, University of California, San Francisco , San Francisco, California 94158, United States. ^[1]

主题词结晶学, X线(Crystallography, X-Ray);药物设计(Drug Design);人类(Humans);模型, 分子(Models, Molecular);蛋白激酶抑制剂(Protein Kinase Inhibitors);蛋白激酶类(Protein Kinases)

DOI 10.1021/cb400376p

PMID 23841803

发布时间 2021-10-21

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