换一批
换一批Henryin, an ent-kaurane diterpenoid, inhibits Wnt signaling through interference with β-catenin/TCF4 interaction in colorectal cancer cells.
作者：
主题词
碱性螺旋-环-螺旋亮氨酸拉链转录因子类(Basic Helix-Loop-Helix Leucine Zipper Transcription Factors);印迹法, 蛋白质(Blotting, Western);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);结直肠肿瘤(Colorectal Neoplasms);二萜类, 贝壳杉烷(Diterpenes, Kaurane);剂量效应关系, 药物(Dose-Response Relationship, Drug);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HCT116细胞(HCT116 Cells);HT29细胞(HT29 Cells);人类(Humans);分子结构(Molecular Structure);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);蛋白质结合(Protein Binding);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);构效关系(Structure-Activity Relationship);时间因素(Time Factors);转录因子(Transcription Factors);β连环素(beta Catenin)
DOI
10.1371/journal.pone.0068525
PMID
23844215
发布时间
2021-10-21
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