换一批
换一批Structural determinants of DISC function: new insights into death receptor-mediated apoptosis signalling.
作者：
关键词
ALPSASMAcidic sphingomyelinaseApoptosisAutoimmune lymphoproliferative syndromeCRDCellular FLICE inhibitory proteinCellular inhibitor of apoptosis proteinCrystal structureCysteine rich domainDDDEDDISCDRDeath domainDeath effector domainDeath receptorDeath-inducing signalling complexEDA (EDA-A1)EDAREDAR-associated death domainEDARADDEctodysplasin AEctodysplasin A receptorFADDFAS Associated Death Domain containing proteinFas receptor ligandFasLIKKIRAKInhibitor of kappa B kinaseInhibitor of kappa-B proteinInterleukin-1 receptor-associated kinaseIκBJNKMAPKMitogen activated protein kinaseNF-κBNuclear factor-kBPARPPI3KPIDDPLADPYDPhosphatidylinositol 3-kinasePoly ADP ribose polymerasePosttranslational modificationPre-Ligand Assembly DomainPyrin DomainsRIP1 (RIPK1)Receptor interacting protein kinase 1SMSphingomyelinaseTAB2TAK1-binding protein 2TL1ATNFTNF Receptor Associated Death Domain proteinTNF receptor-associated factorTNF-like ligand 1ATNFR1 (p55)TRADDTRAFTRAIL (Apo2L)Tumour necrosis factorTumour necrosis factor receptor 1Tumour necrosis factor-related apoptosis-inducing ligandc-Jun N-terminal kinasecFLIPcIAPp53-Induced Death Domainp75 neurotrophin receptorp75(NTR)
主题词
动物(Animals);细胞凋亡(Apoptosis);死亡结构域受体信号接头蛋白质类(Death Domain Receptor Signaling Adaptor Proteins);人类(Humans);蛋白质加工, 转译后(Protein Processing, Post-Translational);受体, 死亡结构域(Receptors, Death Domain);信号传导(Signal Transduction)
DOI
10.1016/j.pharmthera.2013.06.009
PMID
23845861
发布时间
2013-10-07
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