换一批
换一批An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1.
第一作者：
Iris,Grossman
第一单位：
Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel.
作者：
关键词
5,5′-dithiobis-(2-nitrobenzoic acid)BMBSACDRDTNBECMEDTAERErvErv-foldFADHRPHsQSOX1LC–MS/MSLOXPBSPBS with 0.1 TweenPBS-TPDBPEGProtein Data BankQSOX1RTTrxanti-metastatic drugsbasement membranebovine serum albumincomplementarity-determining regiondisulfide bondsendoplasmic reticulumethylenediaminetetraacetic acidextracellular matrixflavin adenine dinucleotidehorseradish peroxidaselamininliquid chromatography–tandem mass spectrometrylysyl oxidasemonoclonal antibodyphosphate-buffered salinepolyethylene glycolquiescin sulfhydryl oxidase 1rdRNaserecombinant human QSOX1reduced and denatured RNase Aroom temperaturescFvsingle-chain variable fragmentthioredoxin-fold
主题词
氨基酸序列(Amino Acid Sequence);抗体, 封闭(Antibodies, Blocking);抗体, 单克隆(Antibodies, Monoclonal);结合部位(Binding Sites);细胞黏附(Cell Adhesion);细胞运动(Cell Movement);二硫化物类(Disulfides);人类(Humans);动力学(Kinetics);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);多蛋白复合物(Multiprotein Complexes);作用于硫族供体的氧化还原酶类(Oxidoreductases Acting on Sulfur Group Donors);蛋白质结合(Protein Binding);蛋白质构象(Protein Conformation);蛋白质相互作用域和基序(Protein Interaction Domains and Motifs);单链抗体(Single-Chain Antibodies);甲苯(Toluene)
DOI
10.1016/j.jmb.2013.07.011
PMID
23867277
发布时间
2015-11-19
- 浏览124
Journal of molecular biology
4366-78页
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