换一批
换一批Dermal absorption and hydrolysis of methylparaben in different vehicles through intact and damaged skin: using a pig-ear model in vitro.
第一作者：
Silvia,Pažoureková
第一单位：
Slovak University of Technology, Faculty of Chemical and Food Technology, Laboratories of Cosmetology, Bratislava, Slovak Republic.
作者：
关键词
ADANOVABLOQBPCIREEPEU Scientific Committee on Consumer SafetyFDAFTSFood and Drug AdministrationHydrolysisIn vitro dermal absorptionIntact and damaged pig-ear skinJ(ss)LODLOQMPMetabolismMetylparabenOECDOrganization for Economic Co-operation and DevelopmentPPGPHBAPPPermeation enhancerRFSCSCCSSDSEDTCTECTranscutol? CGURUS Cosmetic Ingredient Reviewapplied dosebelow the limit of quantificationbutylparabenenhancerethylparabenfull-thickness skin membranelimit of detectionlimit of quantificationmethylparabenone-way analysis of variancep-hydroxybenzoic acidpermeability coefficientpropylene glycolpropylparabenreceptor fluidstandard deviationsteady state fluxstratum corneumsystemic exposure dosagetranscutaneous electrical conductivityunmMPunmetabolised MPurea
主题词
屠宰场(Abattoirs);投药, 皮肤(Administration, Cutaneous);动物(Animals);生物转化(Biotransformation);低温保存(Cryopreservation);皮肤科用药(Dermatologic Agents);耳(Ear);乳状剂(Emulsions);女(雌)性(Female);人类(Humans);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);男(雄)性(Male);对羟苯甲酸类(Parabens);药物赋形剂(Pharmaceutical Vehicles);防腐剂, 药物(Preservatives, Pharmaceutical);皮肤(Skin);皮肤吸收(Skin Absorption);野猪(Sus scrofa)
DOI
10.1016/j.fct.2013.07.025
PMID
23872132
发布时间
2017-11-16
- 浏览108
Food and chemical toxicology
754-65页
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