换一批
换一批Exposure to inhaled particulate matter activates early markers of oxidative stress, inflammation and unfolded protein response in rat striatum.
第一作者：
R,Guerra
第一单位：
Department of Toxicology, CINVESTAV-IPN, México, DF, Mexico.
作者：
关键词
ATF6BiPCentral nervous systemGSMAHO-1IL-1βIRE1αInflammationNF-κBNrf-2Oxidative stressPAHsPERKPMParticulate matterSODStriatumTNFαUPRUnfolded protein responseVACESX-box binding protein 1XBP-1XBP-1 spliced formXBP-1 unspliced formXBP-1SXBP-1Uactivating transcription factor 6eukaryotic translation initiation factor 2-alpha kinase 3gel shift mobility assayheat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)heme oxygenase 1inositol-requiring protein 1interleukin 1 betanuclear factor (erythroid-derived 2)-like 2nuclear factor kappa-light-chain-enhancer of activated B cellsparticulate matterpolycyclic aromatic hydrocarbonssuperoxide dismutasetumor necrosis factor-alphaunfolded protein responseversatile aerosol concentrator system
主题词
空气污染物(Air Pollutants);动物(Animals);中枢神经系统药物(Central Nervous System Agents);纹状体(Corpus Striatum);DNA结合蛋白质类(DNA-Binding Proteins);热休克蛋白质类(Heat-Shock Proteins);血红素氧化酶(脱环)(Heme Oxygenase (Decyclizing));男(雄)性(Male);墨西哥(Mexico);神经组织蛋白质类(Nerve Tissue Proteins);神经元(Neurons);氧化性应激(Oxidative Stress);粒子大小(Particle Size);颗粒物(Particulate Matter);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);超氧化物歧化酶(Superoxide Dismutase);转录因子(Transcription Factors);非折叠蛋白质应答(Unfolded Protein Response);增量调节(Up-Regulation)
DOI
10.1016/j.toxlet.2013.07.012
PMID
23892126
发布时间
2021-12-03
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Toxicology letters
146-54页
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