换一批
换一批A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome.
作者：
关键词
CATSCCHCMTCathepsin SDLSDacryoadenitisELPElastin like-PolypeptideElastin like-polypeptideFK506 binding proteinFKBP-S48I48FKBP12FSIIFNγITCLGNODNon obese diabetic mouseR(h)RapaRapamycinSGSjSSj?gren's syndromeTtcarbacholcathepsin Scritical micelle temperaturedynamic light scatteringhydrodynamic radiii.p.interferon gammaintraperitonealinverse transition cyclinglacrimal glandmTORmammalian target of Rapamycinrapamycinsalivary glandtransition temperature
主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);泪囊炎(Dacryocystitis);药物载体(Drug Carriers);弹性蛋白(Elastin);女(雌)性(Female);免疫抑制剂(Immunosuppressive Agents);泪器(Lacrimal Apparatus);男(雄)性(Male);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);分子序列数据(Molecular Sequence Data);纳米粒子(Nanoparticles);肽类(Peptides);重组融合蛋白质类(Recombinant Fusion Proteins);西罗莫司(Sirolimus);干燥综合征(Sjogren's Syndrome);他克莫司结合蛋白质1A(Tacrolimus Binding Protein 1A)
DOI
10.1016/j.jconrel.2013.07.016
PMID
23892265
发布时间
2021-10-21
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