换一批
换一批Caffeic acid phenethyl ester activation of Nrf2 pathway is enhanced under oxidative state: structural analysis and potential as a pathologically targeted therapeutic agent in treatment of colonic inflammation.
第一作者：
Hyunjeong,Kim
第一单位：
College of Pharmacy, Pusan National University, Busan 609-735, Republic of Korea.
作者：
关键词
2,4,6-Trinitrobenzene sulfonic acid3-phenylpropionic acid phenethyl esterAREAntioxidant response elementBTCABTDHHCBTDMCBiotin-tagged caffeic acidBiotin-tagged dihydroxydihydrocinnamic acidBiotin-tagged dimethoxycinnamic acidCAPECaffeic acid phenethyl esterDHHCDMCDMHCDihydrohydroxycinnamic acid phenethyl esterDimethoxycinnamic acid phenethyl esterDimethoxydihydrocinnamic acid phenethyl esterElectrophileHBSSHank′s buffered salt solutionKeap1Kelch-like ECH associated protein 1MPONrf2Nuclear factor-erythroid 2 p45 (NF-E2)-related factor 2Oxidation of catecholPPAPEPathologically targeted therapeutic agentStructural analysisTNBSmyeloperoxidase
主题词
动物(Animals);消炎药(Anti-Inflammatory Agents);印迹法, 蛋白质(Blotting, Western);咖啡酸类(Caffeic Acids);细胞系, 肿瘤(Cell Line, Tumor);色谱法, 高压液相(Chromatography, High Pressure Liquid);结肠炎(Colitis);疾病模型, 动物(Disease Models, Animal);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);人类(Humans);免疫沉淀法(Immunoprecipitation);NF-E2相关因子2(NF-E2-Related Factor 2);氧化性应激(Oxidative Stress);苯乙基醇(Phenylethyl Alcohol);大鼠(Rats);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.freeradbiomed.2013.07.015
PMID
23892357
发布时间
2018-09-06
- 浏览14
Free radical biology & medicine
552-562页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
