Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection.-论文-万方医学网

第一作者： Cindy,Tamminga

第一单位： Naval Medical Research Center; Silver Spring, MD USA.

作者： Cindy,Tamminga ^[1] ; Martha,Sedegah ^[1] ; Santina,Maiolatesi ^[1] ; Charlotte,Fedders ^[1] ; Sharina,Reyes ^[1] ; Anatalio,Reyes ^[1] ; Carlos,Vasquez ^[1] ; Yolanda,Alcorta ^[1] ; Ilin,Chuang ^[1] ; Michele,Spring ^[2] ; Michael,Kavanaugh ^[3] ; Harini,Ganeshan ^[1] ; Jun,Huang ^[1] ; Maria,Belmonte ^[1] ; Esteban,Abot ^[1] ; Arnel,Belmonte ^[1] ; Joglenna,Banania ^[1] ; Fouzia,Farooq ^[1] ; Jittawadee,Murphy ^[4] ; Jack,Komisar ^[4] ; Nancy O,Richie ^[4] ; Jason,Bennett ^[4] ; Keith,Limbach ^[1] ; Noelle B,Patterson ^[1] ; Joseph T,Bruder ^[5] ; Meng,Shi ^[4] ; Edward,Miller ^[3] ; Sheetij,Dutta ^[4] ; Carter,Diggs ^[6] ; Lorraine A,Soisson ^[6] ; Michael R,Hollingdale ^[1] ; Judith E,Epstein ^[1] ; Thomas L,Richie ^[1]

作者单位： Naval Medical Research Center; Silver Spring, MD USA. ^[1] Armed Forces Research Institute of Medical Sciences; Bangkok, Thailand. ^[2] National Naval Medical Center; Bethesda, MD USA. ^[3] Walter Reed Army Institute of Research; Silver Spring, MD USA. ^[4] GenVec Inc.; Gaithersburg, MD USA. ^[5] USAID; Washington, DC USA. ^[6]

医学主题词腺病毒, 人(Adenoviruses, Human);青少年(Adolescent);成年人(Adult);抗体, 原虫(Antibodies, Protozoan);抗原, 原虫(Antigens, Protozoan);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);酶联免疫斑点测定(Enzyme-Linked Immunospot Assay);女(雌)性(Female);遗传载体(Genetic Vectors);人类(Humans);注射, 肌肉内(Injections, Intramuscular);干扰素γ(Interferon-gamma);白细胞, 单核(Leukocytes, Mononuclear);疟疾疫苗(Malaria Vaccines);疟疾, 恶性(Malaria, Falciparum);男(雄)性(Male);膜蛋白质类(Membrane Proteins);中年人(Middle Aged);恶性疟原虫(Plasmodium falciparum);原虫蛋白质类(Protozoan Proteins);疫苗, 合成(Vaccines, Synthetic);青年人(Young Adult)

DOI 10.4161/hv.24941

PMID 23899517

发布时间 2021-10-21

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Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection.

Human vaccines & immunotherapeutics

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Human vaccines & immunotherapeutics

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Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection.

Human vaccines & immunotherapeutics

相似文献

同项目论文

Human vaccines & immunotherapeutics

相关期刊

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