The LIM domain only 4 protein is a metabolic responsive inhibitor of protein tyrosine phosphatase 1B that controls hypothalamic leptin signaling.
作者:
主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);肾上腺(Adrenal Glands);动物(Animals);细菌蛋白质类(Bacterial Proteins);血压(Blood Pressure);体重(Body Weight);细胞系, 转化(Cell Line, Transformed);胆甾烷类(Cholestanes);内质网(Endoplasmic Reticulum);葡糖耐量试验(Glucose Tolerance Test);内环境稳定(Homeostasis);下丘脑(Hypothalamus);输注, 脑室内(Infusions, Intraventricular);胰岛素抗药性(Insulin Resistance);瘦素(Leptin);发光蛋白质类(Luminescent Proteins);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);去甲肾上腺素(Norepinephrine);胰腺(Pancreas);蛋白质酪氨酸磷酸酶, 非受体1型(Protein Tyrosine Phosphatase, Non-Receptor Type 1);大鼠(Rats);信号传导(Signal Transduction);精胺(Spermine)
DOI
10.1523/JNEUROSCI.0746-13.2013
PMID
23904601
发布时间
2021-10-21
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The Journal of neuroscience
12647-55页
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