Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food.
作者:
关键词
(+)-[2′,6′-(3)H(n)]-methamphetamine(+)-amphetamine(+)-methamphetamineAMPCysDrug abuseFIFRHSMO9HaptenIC(KLH)IC(KLH)-CysIC(KLH)-SMO9K(d)KLHL-cysteineLC–MS/MSMCVMETHMETH-conjugate vaccineMethamphetaminePreclinical studiesREDRatsVaccine[(3)H]-METHequilibrium dissociation constantfixed-interval schedule of behavioral reinforcementfixed-ratio schedule of behavioral reinforcementimmunocyanin monomers derived from native KLHkeyhole limpet hemocyaninliquid chromatography coupled to tandem mass spectrometrymAbmaleimide activated immunocyanin end capped with cysteinemonoclonal antibodyrapid equilibrium dialysisthe METH-conjugate vaccinethe METH-like hapten (S)-N-(2-(mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide
主题词
动物(Animals);男(雄)性(Male);甲基苯丙胺(Methamphetamine);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);物质相关性障碍(Substance-Related Disorders);治疗结果(Treatment Outcome);接种(Vaccination);疫苗, 结合(Vaccines, Conjugate)
DOI
10.1016/j.vaccine.2013.07.038
PMID
23906885
发布时间
2021-10-21
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Vaccine
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