Early epigenetic downregulation of WNK2 kinase during pancreatic ductal adenocarcinoma development.-论文-万方医学网

第一作者： C,Dutruel

第一单位： Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

作者： C,Dutruel ^[1] ; F,Bergmann ^[2] ; I,Rooman ^[3] ; M,Zucknick ^[4] ; D,Weichenhan ^[1] ; L,Geiselhart ^[1] ; T,Kaffenberger ^[1] ; P S,Rachakonda ^[5] ; A,Bauer ^[6] ; N,Giese ^[7] ; C,Hong ^[8] ; H,Xie ^[5] ; J F,Costello ^[8] ; J,Hoheisel ^[6] ; R,Kumar ^[5] ; M,Rehli ^[9] ; P,Schirmacher ^[2] ; J,Werner ^[7] ; C,Plass ^[1] ; O,Popanda ^[1] ; P,Schmezer ^[1]

作者单位： Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[1] Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. ^[2] Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Australia. ^[3] Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[4] Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[5] Functional Genome Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[6] Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany. ^[7] Brain Tumor Research Center, Department of Neurosurgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA. ^[8] Department of Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany. ^[9]

医学主题词动物(Animals);癌, 胰腺管(Carcinoma, Pancreatic Ductal);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);CpG岛(CpG Islands);DNA甲基化(DNA Methylation);减量调节(Down-Regulation);后成说, 遗传(Epigenesis, Genetic);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);胰腺肿瘤(Pancreatic Neoplasms);胰腺炎, 慢性(Pancreatitis, Chronic);启动区, 遗传(Promoter Regions, Genetic);RNA, 信使(RNA, Messenger)

DOI 10.1038/onc.2013.312

PMID 23912455

发布时间 2021-12-03

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Early epigenetic downregulation of WNK2 kinase during pancreatic ductal adenocarcinoma development.

Oncogene

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Oncogene

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Early epigenetic downregulation of WNK2 kinase during pancreatic ductal adenocarcinoma development.

Oncogene

相似文献

同项目论文

Oncogene

相关期刊

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