换一批
换一批
作者：
Michael V,Holmes [1]
;
Tabassome,Simon [2]
;
Holly J,Exeter [3]
;
Lasse,Folkersen [4]
;
Folkert W,Asselbergs [5]
;
Montse,Guardiola [6]
;
Jackie A,Cooper [3]
;
Jutta,Palmen [3]
;
Jaroslav A,Hubacek [7]
;
Kathryn F,Carruthers [8]
;
Benjamin D,Horne [9]
;
Kimberly D,Brunisholz [10]
;
Jessica L,Mega [11]
;
Erik P A,van Iperen [12]
;
Mingyao,Li [13]
;
Maarten,Leusink [14]
;
Stella,Trompet [15]
;
Jeffrey J W,Verschuren [16]
;
G Kees,Hovingh [17]
;
Abbas,Dehghan [18]
;
Christopher P,Nelson [19]
;
Salma,Kotti [20]
;
Nicolas,Danchin [21]
;
Markus,Scholz [22]
;
Christiane L,Haase [23]
;
Dietrich,Rothenbacher [24]
;
Daniel I,Swerdlow [25]
;
Karoline B,Kuchenbaecker [26]
;
Eleonora,Staines-Urias [27]
;
Anuj,Goel [28]
;
Ferdinand,van 't Hooft [4]
;
Karl,Gertow [4]
;
Ulf,de Faire [29]
;
Andrie G,Panayiotou [30]
;
Elena,Tremoli [31]
;
Damiano,Baldassarre [31]
;
Fabrizio,Veglia [32]
;
Lesca M,Holdt [33]
;
Frank,Beutner [34]
;
Ron T,Gansevoort [35]
;
Gerjan J,Navis [35]
;
Irene,Mateo Leach [36]
;
Lutz P,Breitling [37]
;
Hermann,Brenner [37]
;
Joachim,Thiery [38]
;
Dhayana,Dallmeier [39]
;
Anders,Franco-Cereceda [40]
;
Jolanda M A,Boer [41]
;
Jeffrey W,Stephens [42]
;
Marten H,Hofker [43]
;
Alain,Tedgui [44]
;
Albert,Hofman [18]
;
André G,Uitterlinden [45]
;
Vera,Adamkova [7]
;
Jan,Pitha [7]
;
N Charlotte,Onland-Moret [46]
;
Maarten J,Cramer [47]
;
Hendrik M,Nathoe [47]
;
Wilko,Spiering [48]
;
Olaf H,Klungel [14]
;
Meena,Kumari [25]
;
Peter H,Whincup [49]
;
David A,Morrow [11]
;
Peter S,Braund [50]
;
Alistair S,Hall [51]
;
Anders G,Olsson [52]
;
Pieter A,Doevendans [47]
;
Mieke D,Trip [53]
;
Martin D,Tobin [54]
;
Anders,Hamsten [4]
;
Hugh,Watkins [28]
;
Wolfgang,Koenig [39]
;
Andrew N,Nicolaides [55]
;
Daniel,Teupser [33]
;
Ian N M,Day [20]
;
John F,Carlquist [9]
;
Tom R,Gaunt [56]
;
Ian,Ford [57]
;
Naveed,Sattar [58]
;
Sotirios,Tsimikas [59]
;
Gregory G,Schwartz [60]
;
Debbie A,Lawlor [56]
;
Richard W,Morris [61]
;
Manjinder S,Sandhu [60]
;
Rudolf,Poledne [7]
;
Anke H,Maitland-van der Zee [14]
;
Kay-Tee,Khaw [62]
;
Brendan J,Keating [63]
;
Pim,van der Harst [36]
;
Jackie F,Price [64]
;
Shamir R,Mehta [65]
;
Salim,Yusuf [66]
;
Jaqueline C M,Witteman [18]
;
Oscar H,Franco [18]
;
J Wouter,Jukema [67]
;
Peter,de Knijff [68]
;
Anne,Tybjaerg-Hansen [23]
;
Daniel J,Rader [69]
;
Martin,Farrall [28]
;
Nilesh J,Samani [19]
;
Mika,Kivimaki [25]
;
Keith A A,Fox [8]
;
Steve E,Humphries [3]
;
Jeffrey L,Anderson [9]
;
S Matthijs,Boekholdt [53]
;
Tom M,Palmer [70]
;
Per,Eriksson [4]
;
Guillaume,Paré [71]
;
Aroon D,Hingorani [72]
;
Marc S,Sabatine [11]
;
Ziad,Mallat [73]
;
Juan P,Casas [74]
;
Philippa J,Talmud [3]
作者单位：
Faculty of Population Health Sciences, University College London, London, United Kingdom. Electronic address: mvholmes@gmail.com.
[1]
Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Antoine, Department of Clinical Pharmacology, URC-EST, Paris, France; Université Pierre et Marie Curie, Paris, France; INSERM, U 698, Paris, France.
[2]
Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom.
[3]
Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.
[4]
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands; Durrer Center for Cardiogenetic Research, Amsterdam, the Netherlands.
[5]
Unitat de Recerca en Lípids i Arteriosclerosi, IISPV, Universitat Rovira i Virgili, CIBERDEM, Reus, Spain.
[6]
Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
[7]
Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland, United Kingdom.
[8]
Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, Utah; Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
[9]
Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, Utah.
[10]
TIMI Study Group, Divison of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, Massachusetts.
[11]
Durrer Center for Cardiogenetic Research, Amsterdam, the Netherlands; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
[12]
Department of Biostatistics & Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
[13]
Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.
[14]
Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
[15]
Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
[16]
Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
[17]
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Member of the Netherlands Consortium on Healthy Aging (NCHA), Leiden, the Netherlands.
[18]
Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom; Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, United Kingdom.
[19]
Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Antoine, Department of Clinical Pharmacology, URC-EST, Paris, France.
[20]
Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Department of Cardiology, Paris, France; Université Paris Descartes, Paris V, Paris, France.
[21]
Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany; LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
[22]
Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
[23]
Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany; Division of Clinical Epidemiology & Aging Research, German Cancer Research Center, Heidelberg, Germany.
[24]
Faculty of Population Health Sciences, University College London, London, United Kingdom.
[25]
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
[26]
Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.
[27]
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
[28]
Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
[29]
Cyprus Cardiovascular Educational and Research Trust, Nicosia, Cyprus and Cyprus International Institute for Environmental and Public Health in association with the Harvard School of Public Health, Cyprus University of Technology, Limassol, Cyprus.
[30]
Dipartimento di Scienze Farmacologiche e Biomolecolari, Universitá di Milano, Milan, Italy; Centro Cardiologico Monzino, IRCCS, Milan, Italy.
[31]
Centro Cardiologico Monzino, IRCCS, Milan, Italy.
[32]
LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany; Institute of Laboratory Medicine, University Hospital Munich (LMU), Ludwig-Maximilians-University Munich, Munich, Germany.
[33]
LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany; Department of Internal Medicine/Cardiology, Heart Center, University of Leipzig, Leipzig, Germany.
[34]
University Medical Center Groningen, University of Groningen, Department of Internal Medicine, Groningen, the Netherlands.
[35]
University Medical Center Groningen, University of Groningen, Department of Cardiology, Groningen, the Netherlands.
[36]
Division of Clinical Epidemiology & Aging Research, German Cancer Research Center, Heidelberg, Germany.
[37]
LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.
[38]
Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany.
[39]
Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
[40]
Department for Nutrition and Health, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
[41]
Diabetes Research Group, Institute of Life Sciences, College of Medicine, Swansea University, Swansea, Wales, United Kingdom.
[42]
Department of Pathology and Medical Biology, Medical Biology Section, Molecular Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
[43]
Inserm U970, Paris-Cardiovascular Research Center, Paris, France.
[44]
Member of the Netherlands Consortium on Healthy Aging (NCHA), Leiden, the Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
[45]
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands.
[46]
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands.
[47]
Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
[48]
Division of Population Health Sciences and Education, St George's, University of London, London, United Kingdom.
[49]
Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
[50]
Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom.
[51]
Stockholm Heart Center, Stockholm, and Linköping University, Linkőping, Sweden.
[52]
Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
[53]
Departments of Health Sciences & Genetics, University of Leicester, Leicester, United Kingdom.
[54]
Department of Vascular Surgery, Imperial College, London, United Kingdom; Cyprus Cardiovascular Educational and Research Trust, Nicosia, Cyprus.
[55]
MRC Centre for Causal Analyses in Translational Epidemiology (CAiTE), and Bristol Genetic Epidemiology Laboratories (BGEL), School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.
[56]
Robertson Centre for Biostatistics, University of Glasgow, Glasgow, Scotland, United Kingdom.
[57]
British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland, United Kingdom.
[58]
Division of Cardiovascular Diseases, Department of Medicine, University of California San Diego, La Jolla, California.
[59]
VA Medical Center and University of Colorado School of Medicine, Denver, Colorado.
[60]
Department of Primary Care & Population Health, University College London, Royal Free Campus, London, United Kingdom.
[61]
Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
[62]
Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
[63]
Centre for Population Health Sciences, University of Edinburgh, United Kingdom.
[64]
Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Interventional Cardiology, McMaster University, Hamilton, Ontario, Canada; Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.
[65]
Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.
[66]
Durrer Center for Cardiogenetic Research, Amsterdam, the Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands.
[67]
Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
[68]
Preventive Cardiovascular Medicine, Penn Heart and Vascular Center, Philadelphia, Pennsylvania.
[69]
Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
[70]
Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada; Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada; Genetic and Molecular Epidemiology Laboratory, McMaster University, Hamilton, Ontario, Canada.
[71]
Faculty of Population Health Sciences, University College London, London, United Kingdom; Centre for Clinical Pharmacology, Division of Medicine, University College London, London, United Kingdom.
[72]
Inserm U970, Paris-Cardiovascular Research Center, Paris, France; Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.
[73]
Faculty of Population Health Sciences, University College London, London, United Kingdom; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom. Electronic address: Juan.Pablo-Casas@lshtm.ac.uk.
[74]
关键词
ACSCILDL-CMIMVEMendelian randomizationORRCTSNPacute coronary syndrome(s)cardiovascular diseasesconfidence intervaldrug developmentepidemiologygeneticslow-density lipoprotein cholesterolmajor vascular eventsmyocardial infarctionodds ratiorandomized clinical trialsPLA(2)secretory phospholipase A(2)single-nucleotide polymorphism
主题词
等位基因(Alleles);心血管疾病(Cardiovascular Diseases);DNA(DNA);基因表达调控(Gene Expression Regulation);人类(Humans);发病率(Incidence);孟德尔随机化分析(Mendelian Randomization Analysis);磷脂酶A2, 分泌型(Phospholipases A2, Secretory)
DOI
10.1016/j.jacc.2013.06.044
PMID
23916927
发布时间
2024-04-25
- 浏览91
Journal of the American College of Cardiology
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