换一批
换一批Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses.
作者：
主题词
艾滋病疫苗(AIDS Vaccines);动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);抗体, 中和(Antibodies, Neutralizing);抗原, 病毒(Antigens, Viral);B-淋巴细胞(B-Lymphocytes);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);基因敲入技术(Gene Knock-In Techniques);HIV抗体(HIV Antibodies);HIV包膜蛋白质gp41(HIV Envelope Protein gp41);HIV-1(HIV-1);人类(Humans);淋巴细胞活化(Lymphocyte Activation);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);中和试验(Neutralization Tests);T淋巴细胞(T-Lymphocytes)
DOI
10.4049/jimmunol.1300971
PMID
23918977
发布时间
2021-10-21
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