换一批
换一批Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design.
作者：
主题词
动物(Animals);抗体(Antibodies);抗体, 双特异性(Antibodies, Bispecific);抗体特异性(Antibody Specificity);CHO细胞(CHO Cells);色谱法, 液相(Chromatography, Liquid);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);药物设计(Drug Design);人类(Humans);氢离子浓度(Hydrogen-Ion Concentration);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);免疫球蛋白Fc片段(Immunoglobulin Fc Fragments);质谱分析法(Mass Spectrometry);模型, 分子(Models, Molecular);突变(Mutation);蛋白质工程(Protein Engineering);蛋白质多聚化(Protein Multimerization);蛋白质结构, 三级(Protein Structure, Tertiary);静电(Static Electricity);温度(Temperature)
DOI
10.4161/mabs.25632
PMID
23924797
发布时间
2021-10-21
- 浏览80
mAbs
646-54页
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