Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation.
第一作者:
Ilse M,Beck
第一单位:
Laboratory of Experimental Cancer Research (LECR), Department of Radiation Therapy & Experimental Cancer Research, Ghent University, Ghent, Belgium. Ilse.Beck@Ugent.be
作者:
主题词
动物(Animals);消炎药(Anti-Inflammatory Agents);细胞系(Cell Line);DNA结合蛋白质类(DNA-Binding Proteins);剂量效应关系, 药物(Dose-Response Relationship, Drug);女(雌)性(Female);基因表达调控(Gene Expression Regulation);HSP70热休克蛋白质类(HSP70 Heat-Shock Proteins);HSP90热休克蛋白质类(HSP90 Heat-Shock Proteins);人类(Humans);小鼠(Mice);模型, 生物学(Models, Biological);NF-κB(NF-kappa B);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);受体, 糖皮质激素(Receptors, Glucocorticoid);反应元件(Response Elements);转录因子(Transcription Factors);转录激活(Transcriptional Activation)
DOI
10.1371/journal.pone.0069115
PMID
23935933
发布时间
2021-10-21
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