Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells.-论文-万方医学网

作者： Takahiko,Imai ^[1] ; Naoto,Koyanagi ; Ryo,Ogawa ; Keiko,Shindo ; Tadahiro,Suenaga ; Ayuko,Sato ; Jun,Arii ; Akihisa,Kato ; Hiroshi,Kiyono ; Hisashi,Arase ; Yasushi,Kawaguchi

作者单位： Division of Molecular Virology, Department of Microbiology and Immunology, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan. ^[1]

主题词动物(Animals);抗原呈递(Antigen Presentation);抗原, 病毒(Antigens, Viral);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞系(Cell Line);细胞膜(Cell Membrane);酶激活(Enzyme Activation);女(雌)性(Female);基因顺序(Gene Order);基因组, 病毒(Genome, Viral);疱疹病毒1型, 人(Herpesvirus 1, Human);组织相容性抗原Ⅰ类(Histocompatibility Antigens Class I);人类(Humans);杀伤细胞, 天然(Killer Cells, Natural);淋巴细胞去除术(Lymphocyte Depletion);小鼠(Mice);突变(Mutation);磷酰化(Phosphorylation);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic);Vero细胞(Vero Cells);病毒蛋白质类(Viral Proteins);病毒复制(Virus Replication)

DOI 10.1371/journal.pone.0072050

PMID 23951282

发布时间 2021-12-03

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Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells.

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Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells.

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PloS one

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