换一批Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures.
第一作者：
Ronald D,Gorham
第一单位：
Department of Bioengineering, University of California, Riverside, CA 92521, USA.
作者：
关键词
AMDAPApoEC3C3bC3cC5b-9ELISAFBMDPDBRP-HPLCRPEage-related macular degenerationalternative pathway of complement activationapolipoprotein Ecomplement inhibitorscomplement systemcomplement system protein 3compstatin family peptidesdrusenenzyme-linked immunosorbent assayfactor Bmacular degenerationmolecular dynamicsprotein data bankretinal pigmented epitheliumreversed phase high performance liquid chromatographythe b-fragment of C3the c-fragment of C3the membrane attack complex consisting of complement proteins C5b, C6, C7, C8, and C9(n)
医学主题词
细胞, 培养的(Cells, Cultured);补体激活(Complement Activation);人类(Humans);肽类, 环(Peptides, Cyclic);视网膜小疣(Retinal Drusen);视网膜色素上皮(Retinal Pigment Epithelium)
DOI
10.1016/j.exer.2013.07.023
PMID
23954241
发布时间
2021-10-21
基金项目
R01 GM052032/GM/NIGMS NIH HHS/United States
R01-GM052032/GM/NIGMS NIH HHS/United States
- 浏览39
Experimental eye research
96-108页
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