换一批
换一批Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions.
作者：
关键词
ACACSFD1 receptorsD1RsDADA- and cAMP-regulated phosphoprotein of 32?kDaDARPP-32Direct pathwayDopamineForskolinGABAA IPSCsIEIMSNsPDEPKAPPSCHSCH23390SKFSKF38393SNprSubstantia nigra pars reticulataadenylyl cyclaseartificial cerebrospinal fluidcAMPcAMP-dependent protein kinasecyclic adenosine monophosphatedopamineeIPSCsevoked IPSCsforskolinfskinter-event intervalmedium-spiny neuronspaired pulsepapavpapaverinephosphodiesterasesIPSCsspontaneous IPSCssubstantia nigra pars reticulata
主题词
2,3,4,5-四氢-7,8-二羟基-1-苯基-1H-3-苯骈吖庚因(2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine);动物(Animals);纹状体(Corpus Striatum);多巴胺(Dopamine);多巴胺激动剂(Dopamine Agonists);药物相互作用(Drug Interactions);抑制性突触后电位(Inhibitory Postsynaptic Potentials);小鼠(Mice);神经通路(Neural Pathways);羟多巴胺(Oxidopamine);罂粟碱(Papaverine);磷酸二酯酶抑制剂(Phosphodiesterase Inhibitors);磷酸二酯水解酶类(Phosphoric Diester Hydrolases);磷酰化(Phosphorylation);钾(Potassium);受体, 多巴胺D1(Receptors, Dopamine D1);黑质(Substantia Nigra);γ氨基丁酸(gamma-Aminobutyric Acid)
DOI
10.1016/j.neuropharm.2013.08.010
PMID
23973317
发布时间
2018-12-02
- 浏览110
Neuropharmacology
127-36页
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