Altered Th17 cells and Th17/regulatory T-cell ratios indicate the subsequent conversion from undifferentiated connective tissue disease to definitive systemic autoimmune disorders.
作者:
关键词
(Scleroderma-70 antigen, DNA Topoisomerase I)ANAANCAAPCC-reactive proteinCCPCNSCRPELISAENAFITCIL-10 producing Type-1 regulatory T-cellsMCTDNKTPBMCPEPM/DMRARFSAIDSLESSSScScl-70Sj?gren’s syndromeSmSmith antigenT-helper cellTc-DTPAThTr1TregU1 ribonucleoproteinU1RNPUCTDaCLallophycocyaninanti-cardiolipinanti-neutrophil cytoplasmic antibodiesanti-nuclear antibodycentral nervous systemcyclic citrullinated peptidedouble-stranded deoxyribonucleic aciddsDNAenzyme-linked immunosorbent assayextractable nuclear antigenfluorescein isothiocyanatemixed connective tissue diseasenTregnatural killer T cellnatural regulatory T cellperipheral blood mononuclear cellphycoerythrinpolymyositis/dermatomyositisregulatory T cellrheumatoid arthritisrheumatoid factorsystemic autoimmune diseasesystemic lupus erythematosussystemic sclerosistechnetium-diethylene-triamine-pentaacetateundifferentiated connective tissue disease
主题词
成年人(Adult);自身免疫疾病(Autoimmune Diseases);结缔组织疾病(Connective Tissue Diseases);疾病恶化(Disease Progression);女(雌)性(Female);随访研究(Follow-Up Studies);人类(Humans);免疫表型分型(Immunophenotyping);淋巴细胞计数(Lymphocyte Count);中年人(Middle Aged);预后(Prognosis);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);Th17细胞(Th17 Cells)
DOI
10.1016/j.humimm.2013.08.003
PMID
23974054
发布时间
2013-11-26
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Human immunology
1510-8页
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