Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells.
第一作者:
Z,Chen
第一单位:
Department of Molecular Genetics and Microbiology, Shands Cancer Center, University of Florida, Gainesville, FL, USA.
作者:
医学主题词
动物(Animals);癌, 黏液表皮样(Carcinoma, Mucoepidermoid);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);染色体, 人, 11对(Chromosomes, Human, Pair 11);染色体, 人, 19对(Chromosomes, Human, Pair 19);cAMP反应元件结合蛋白质(Cyclic AMP Response Element-Binding Protein);DNA结合蛋白质类(DNA-Binding Proteins);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);糖蛋白类(Glycoproteins);人类(Humans);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);核蛋白质类(Nuclear Proteins);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);蛋白质结合(Protein Binding);信号传导(Signal Transduction);反式激活因子类(Trans-Activators);转录因子(Transcription Factors);转录激活(Transcriptional Activation);易位, 遗传(Translocation, Genetic)
DOI
10.1038/onc.2013.348
PMID
23975434
发布时间
2022-03-10
- 浏览66
Oncogene
3869-77页
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