第一作者:
Jittima,Weerachayaphorn
第一单位:
Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, USA; Department of Physiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
作者:
关键词
ALTANITAhRBADFBAIFBDLBSEPBile secretionCARCK19CMCECMEDTAFXRGSHHSCHepatic stellate cellsIL-1βIL-6Keap1LD50MmpMrpNAD(P)H quinone oxidoreductaseNqoINrf2OPZObstructive cholestasisOltiprazPBCPDGFβPFTGF-β1TNF-αTimpUDCAalanine aminotransferasealpha smooth muscle actinalpha-naphthylisothiocyanatearyl hydrocarbon receptorbile acid-dependent bile flowbile acid-independent bile flowbile duct ligationbile salt efflux pumpcarboxymethylcelluloseconstitutive androstane receptorcytokeratin 19ethylenediaminetetraacetic acidextracellular matrixfarnesoid X receptorglutathionehepatic stellate cellsinterleukin-1 betainterleukin-6kelch-like ECH-associated protein 1lethal dosagematrix metalloproteinasesmultidrug resistance-associated proteinoltiprazplatelet-derived growth factor-betaportal fibroblastsprimary biliary cirrhosistissue inhibitors of metalloproteinasetransforming growth factor-beta 1tumor necrosis factor-alphaursodeoxycholic acidα-SMA
主题词
血管生成蛋白质类(Angiogenic Proteins);动物(Animals);胆汁(Bile);胆汁酸类和盐类(Bile Acids and Salts);胆管(Bile Ducts);胆汁淤积, 肝外(Cholestasis, Extrahepatic);谷胱甘肽(Glutathione);结扎术(Ligation);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);多药耐药相关蛋白质类(Multidrug Resistance-Associated Proteins);NF-E2相关因子2(NF-E2-Related Factor 2);吡嗪类(Pyrazines);硫酮类(Thiones);噻吩类(Thiophenes);转化生长因子β(Transforming Growth Factor beta)
DOI
10.1016/j.jhep.2013.08.015
PMID
23978715
发布时间
2021-10-21
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Journal of hepatology
160-6页
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