Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice.
第一作者:
Viswanathan,Saraswathi
第一单位:
Department of Molecular Physiology and Biophysics; Department of Internal Medicine/Division of Diabetes, Endocrinology, and Metabolism; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center; VA Nebraska Western Iowa Health Care System, Omaha, NE. Electronic address: s.viswanathan@unmc.edu.
作者:
关键词
3-hydroxy-3-methyl-glutaryl-CoA reductase4′,6-diamidino-2-phenylindole;F4/80, murine homologue of EGF-like module-containing mucin-like hormone receptor-like 1AMPKATBMTCC chemokine receptor-2CC chemokine receptor-5CCR2CCR5CD68COXCOX-1 knock-outCOX-1+/+COX-1?/?CPT-1DAPIDyslipidemiaEicosanoidsFASNFBP-1G6PCGAPDHGC/MSGSKGlut-4HMGCRHOMA-IRHyperglycemiaILIR-βL-FABPLDLRMCP-1MGLMIP-1αMMP-12NMRObesityPCK-1 and PEPCKPCXPGSAA-3SGLT-2SVCTLR4TNFαTXadenosine monophosphate-activated protein kinaseadipose tissueapoEapolipoprotein Ebone marrow transplantationcarnitine palmitoyl transferase-1cluster of differentiation 68cyclooxygenasefatty acid synthasefructose 1,6 bisphosphatasegas chromatography/mass spectrometryglucose transporter-4glucose-6-phosphataseglyceraldehyde 3 phosphate dehydrogenaseglycogen synthase kinasehomeostasis model assessment of insulin resistanceinterleukinliver fatty acid binding proteinlow density lipoprotein receptormacrophage galactose type lectinmacrophage inflammatory protein-1αmatrix metalloproteinase-12monocyte chemoattractant proteinnuclear magnetic resonancephospho insulin receptor betaphosphoenol pyruvate carboxykinaseprostaglandinpyruvate carboxylaseserum amyloid A-3sodium glucose cotransporter-2stromal vascular cellsthromboxanetoll-like receptor 4tumor necrosis factor alphawild type
医学主题词
脂联素(Adiponectin);脂肪组织(Adipose Tissue);动物(Animals);印迹法, 蛋白质(Blotting, Western);骨髓细胞(Bone Marrow Cells);骨髓移植(Bone Marrow Transplantation);环氧化酶1(Cyclooxygenase 1);进食(Eating);女(雌)性(Female);荧光抗体技术(Fluorescent Antibody Technique);炎症(Inflammation);肾(Kidney);瘦素(Leptin);肝(Liver);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);肥胖症(Obesity);体重增长(Weight Gain)
DOI
10.1016/j.metabol.2013.07.007
PMID
23987235
发布时间
2021-10-21
- 浏览104
Metabolism
1673-85页
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