An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.

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作者： Amrita,Basu ^[1] ; Nicole E,Bodycombe ^[1] ; Jaime H,Cheah ^[1] ; Edmund V,Price ^[1] ; Ke,Liu ^[1] ; Giannina I,Schaefer ^[1] ; Richard Y,Ebright ^[1] ; Michelle L,Stewart ^[1] ; Daisuke,Ito ^[1] ; Stephanie,Wang ^[1] ; Abigail L,Bracha ^[1] ; Ted,Liefeld ^[1] ; Mathias,Wawer ^[1] ; Joshua C,Gilbert ^[1] ; Andrew J,Wilson ^[2] ; Nicolas,Stransky ^[1] ; Gregory V,Kryukov ^[1] ; Vlado,Dancik ^[1] ; Jordi,Barretina ^[1] ; Levi A,Garraway ^[1] ; C Suk-Yee,Hon ^[1] ; Benito,Munoz ^[1] ; Joshua A,Bittker ^[1] ; Brent R,Stockwell ^[3] ; Dineo,Khabele ^[2] ; Andrew M,Stern ^[1] ; Paul A,Clemons ^[4] ; Alykhan F,Shamji ^[5] ; Stuart L,Schreiber ^[6]

作者单位： The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. ^[1] Vanderbilt University School of Medicine, Nashville, TN 37232, USA. ^[2] Columbia University, New York, NY 10027, USA. ^[3] The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: pclemons@broadinstitute.org. ^[4] The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: ashamji@broadinstitute.org. ^[5] The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: stuart_schreiber@harvard.edu. ^[6]

主题词抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);药物发现(Drug Discovery);人类(Humans);肿瘤(Neoplasms)

DOI 10.1016/j.cell.2013.08.003

PMID 23993102

发布时间 2022-03-18

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