Modeling the estrogen receptor to growth factor receptor signaling switch in human breast cancer cells.
作者:
关键词
17β-estradiolAKTBreast cancerCCSCSCE2E2-bound estrogen receptorE2:EREGFRERER-PEndocrine resistanceEstrogen receptor signalingFCSGFRGrowth factor receptor signalingHER2MAPKMathematical modelingNFκBPI3Ka serine/threonine-specific protein kinase, also known as Protein Kinase B (PKB)cancer stem cellcharcoal-stripped fetal-calf serumepidermal growth factor receptorestrogen receptorfetal calf serumgrowth factor receptorhuman epidermal growth factor receptor-2mTORmammalian target of rapamycinmitogen activated protein kinasesnuclear factor kappa-light-chain-enhancer of activated B cellsphosphatidylinositide 3-kinasesphosphorylated estrogen receptor
主题词
乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);雌激素类(Estrogens);女(雌)性(Female);人类(Humans);模型, 理论(Models, Theoretical);受体, 雌激素(Receptors, Estrogen)
DOI
10.1016/j.febslet.2013.08.022
PMID
23994522
发布时间
2021-10-21
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FEBS letters
3327-34页
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