换一批
换一批Metformin suppresses hepatocellular carcinoma cell growth through induction of cell cycle G1/G0 phase arrest and p21CIP and p27KIP expression and downregulation of cyclin D1 in vitro and in vivo.
第一作者：
Xianbin,Cai
第一单位：
Department of Gastroenterology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
作者：
主题词
氨基咪唑甲酰胺(Aminoimidazole Carboxamide);动物(Animals);癌, 肝细胞(Carcinoma, Hepatocellular);细胞存活(Cell Survival);细胞周期蛋白D1(Cyclin D1);周期素依赖激酶抑制剂p21(Cyclin-Dependent Kinase Inhibitor p21);周期素依赖激酶抑制剂p27(Cyclin-Dependent Kinase Inhibitor p27);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);Hep G2细胞(Hep G2 Cells);人类(Humans);肝肿瘤(Liver Neoplasms);二甲双胍(Metformin);小鼠(Mice);核糖核苷酸类(Ribonucleotides);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.3892/or.2013.2718
PMID
24008375
发布时间
2022-03-31
- 浏览43
Oncology reports
2449-57页
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