换一批Regulated in DNA damage and development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1).
第一作者：
Michael D,Dennis
第一单位：
Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.
作者：
关键词
4E-BP170-kDa ribosomal protein S6 kinase 1ATF4AutophagyDDIT4ERKFBSGCN2IGF1LC3PERKREDD1Rtp801ULK1UNC-51-like kinase 1X-box binding protein 1XBP1activating transcription factor 4autophagy marker light chain 3caconstitutively activedndominant negativeeukaryotic initiation factor 4E binding protein 1extracellular signal-related protein kinasefetal bovine serumgeneral control non-derepressing 2insulin-like growth factor 1mTORC1mammalian target of rapamycin in complex 1p70S6K1protein kinase RNA-like endoplasmic reticulum kinaseregulated in DNA damage and development 1
医学主题词
转录激活因子4(Activating Transcription Factor 4);动物(Animals);自噬(Autophagy);细胞系(Cell Line);细胞存活(Cell Survival);DNA损伤(DNA Damage);多蛋白复合物(Multiprotein Complexes);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);大鼠(Rats);阻遏蛋白质类(Repressor Proteins);血清(Serum);信号传导(Signal Transduction);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);转录因子(Transcription Factors);转录激活(Transcriptional Activation)
DOI
10.1016/j.cellsig.2013.08.038
PMID
24018049
发布时间
2021-12-03
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Cellular signalling
2709-16页
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