换一批Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.
第一作者：
Nikolaj H T,Petersen
第一单位：
Department of Cell Death and Metabolism, Danish Cancer Society Research Center (DCRC), DK-2100 Copenhagen, Denmark.
作者：
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞死亡(Cell Death);细胞系, 肿瘤(Cell Line, Tumor);细胞转化, 肿瘤(Cell Transformation, Neoplastic);抗药性, 肿瘤(Drug Resistance, Neoplasm);酶激活(Enzyme Activation);酶抑制剂(Enzyme Inhibitors);女(雌)性(Female);HSP70热休克蛋白质类(HSP70 Heat-Shock Proteins);人类(Humans);吲哚类(Indoles);溶酶体(Lysosomes);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);表型(Phenotype);鞘脂类(Sphingolipids);鞘磷脂磷酸二酯酶(Sphingomyelin Phosphodiesterase);螺环化合物(Spiro Compounds);生育酚类(Tocopherols);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1016/j.ccr.2013.08.003
PMID
24029234
发布时间
2024-07-24
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Cancer cell
379-93页
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