换一批Radiochemical and radiobiological assessment of a pyridyl-S-cysteine functionalized bombesin derivative labeled with the (99m)Tc(CO)3(+) core.
第一作者：
Penelope,Bouziotis
第一单位：
Institute of Nuclear and Radiological Sciences and Technology, Energy and Safety, N.C.S.R. 'Demokritos', 15310 Aghia Paraskevi, Greece. Electronic address: bouzioti@rrp.demokritos.gr.
作者：
关键词
1-hydroxybenzotriazole9-fluorenylmethyloxycarbonylBSABocBombesinCysDICDIEADMEMDMFDulbecco’s modified Eagle mediumEDTAESI-MSEtOHFBSFmocHOBtI.D.IDN,N-diisopropylethylaminePBSPETPMSFPSPMTROIRP/SE-HPLCRTRadiolabelingRadiopharmaceuticalsSCIDSPECTSPPSTFATIPSTechnetiumTricarbonyl precursorbovine serum albumincysteinediisopropylcarbamidedimethylformamideelectrospray ionization mass spectrometryethanolethylenediaminetetraacetic acidfetal bovine seruminjected doseinternal diameterintravenousivp.i.phenylmethanesulfonyl fluoridephosphate buffered salineposition sensitive photomultiplier tubepositron emission tomographypostinjectionregions of interestreversed-phase/size-exclusion high-performance liquid chromatographyroom temperaturesevere combined immunodeficiencysingle photon emission computerized tomographysolid phase peptide synthesist-butyloxycarbonyltrifluoroacetic acidtriisopropylsilane
医学主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);铃蟾肽(Bombesin);细胞系, 肿瘤(Cell Line, Tumor);半胱氨酸(Cysteine);人类(Humans);小鼠(Mice);小鼠, SCID(Mice, SCID);肿瘤(Neoplasms);有机锝化合物(Organotechnetium Compounds);肽类(Peptides);放射性药物(Radiopharmaceuticals);受体, 铃蟾肽(Receptors, Bombesin);组织分布(Tissue Distribution);体层摄影术, 发射型计算机, 单光子(Tomography, Emission-Computed, Single-Photon)
DOI
10.1016/j.bmc.2013.08.010
PMID
24035515
发布时间
2016-11-25
- 浏览205
Bioorganic & medicinal chemistry
6699-707页
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