Disturbance of brain energy and redox homeostasis provoked by sulfite and thiosulfate: potential pathomechanisms involved in the neuropathology of sulfite oxidase deficiency.
作者:
关键词
2,6-dichloroindophenol2′,7′-dichlorofluorescein diacetate2′,7′-dichlorofluorescinBioenergetic dysfunctionCKDCFDCF-DADCFHDCIPGSHL-NAMEMELN(ω)-nitro-l-arginine methyl esterPiROSRat brainReactive speciesSOSulfiteSulfite oxidase deficiencyTROThiosulfatecCKcreatine kinasecytosolic creatine kinasedichlorofluoresceininorganic phosphatemCKmelatoninmitochondrial creatine kinasereactive oxygen speciesreduced glutathionesulfite oxidasetCKtotal creatine kinasetrolox
主题词
氨基酸代谢障碍, 先天性(Amino Acid Metabolism, Inborn Errors);动物(Animals);脑(Brain);脑疾病, 代谢性(Brain Diseases, Metabolic);电子转运(Electron Transport);能量代谢(Energy Metabolism);内环境稳定(Homeostasis);男(雄)性(Male);氧化还原(Oxidation-Reduction);大鼠(Rats);大鼠, Wistar(Rats, Wistar);亚硫酸氧化酶(Sulfite Oxidase);亚硫酸盐类(Sulfites);硫代硫酸盐类(Thiosulfates)
DOI
10.1016/j.gene.2013.09.018
PMID
24035933
发布时间
2013-10-15
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Gene
191-8页
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