换一批
换一批
第一作者：
Lucie,Maingot
第一单位：
INSERM U761, Biostructures and Drug Discovery, France; Faculté de Pharmacie, Univ Lille Nord de France, 3 rue du Pr Laguesse, Lille F-59006, France; Institut Pasteur de Lille, IFR 142, Lille F-59021, France; PRIM, Lille F-59006, France.
作者：
关键词
3,3′,5,5′-tetramethylbenzidineADAMTS-5AcOHAcylthiosemicarbazideAggrecanaseBocCH(3)CNDCEDCMDIEADMFDMPDMSODess–Martin periodinaneEDCIEt(3)NEtOAcEtOHHOBtLibraryMeOHN,N-diisopropylethylamineN-ethyl-3-(3-dimethylaminopropyl)carbodiimideN-hydroxybenzotriazoleOAPBSPTSASARTACETHFTMBa disintegrin and metalloproteinase with thrombospondin motifs 5acetic acidacetonitriledichloroethanedichloromethanedimethylformamidedimethylsulfoxideethanolethyl acetatemethanolosteoarthritispara-toluenesulfonic acidphosphate buffered salineroom temperaturertstructure–activity relationshiptert-butoxycarbonyltetrahydrofurantriethylaminetumor necrosis factor-α-converting enzyme
主题词
ADAM蛋白质类(ADAM Proteins);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物设计(Drug Design);酶抑制剂(Enzyme Inhibitors);人类(Humans);模型, 分子(Models, Molecular);分子结构(Molecular Structure);有机金属化合物(Organometallic Compounds);氨基脲类(Semicarbazides);构效关系(Structure-Activity Relationship);锌(Zinc)
DOI
10.1016/j.ejmech.2013.08.027
PMID
24044937
发布时间
2016-11-25
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