换一批
换一批Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.
作者：
主题词
动物(Animals);人类(Humans);肺(Lung);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);核蛋白质类(Nuclear Proteins);过氧化物酶类(Peroxidases);肺疾病, 慢性阻塞性(Pulmonary Disease, Chronic Obstructive);肺气肿(Pulmonary Emphysema);受体, 血小板源生长因子β(Receptor, Platelet-Derived Growth Factor beta);信号传导(Signal Transduction);烟(Smoke);超氧化物类(Superoxides);增量调节(Up-Regulation)
DOI
10.1242/dmm.013482
PMID
24046361
发布时间
2022-06-24
- 浏览17
Disease models & mechanisms
1378-87页
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