Effects of prolonged selective serotonin reuptake inhibition on the development and expression of L-DOPA-induced dyskinesia in hemi-parkinsonian rats.
作者:
关键词
3,4-dihydroxyphenylacetic acid5-HIAA5-HT5-HT(1A) receptor5-hydroxyindoleacetic acid6-OHDA6-hydroxydopamineAIMsALOAbnormal involuntary movementsAxial, limb and orolingualBenserazideDADATDL-serine 2-(2,3,4-trihydroxybenzyl) hydrazine hydrochlorideDMSODOPACDimethyl sulfoxideDopamineDopamine transporterFASForepaw adjusting steps testHPLCHigh performance liquid chromatographyLIDMFBMedial forebrain bundleN-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate saltNENorepinephrinePDParkinson's diseaseSERTSSRISelective 5-HT reuptake inhibitorSelective serotonin reuptake inhibitorSerotoninSerotonin transporterWAY100635l-DOPA-induced dyskinesia
主题词
动物(Animals);西酞普兰(Citalopram);纹状体(Corpus Striatum);多巴胺(Dopamine);运动障碍, 药物性(Dyskinesia, Drug-Induced);左旋多巴(Levodopa);男(雄)性(Male);运动活动(Motor Activity);羟多巴胺(Oxidopamine);帕金森病, 继发性(Parkinson Disease, Secondary);帕罗西汀(Paroxetine);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley)
DOI
10.1016/j.neuropharm.2013.09.017
PMID
24067924
发布时间
2022-12-07
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