换一批
换一批Docosahexaenoic acid (DHA)-induced heme oxygenase-1 attenuates cytotoxic effects of DHA in vascular smooth muscle cells.
第一作者：
Gabriel,Stulnig
第一单位：
Institute of Molecular Biology and Biochemistry, Center of Molecular Medicine, Medical University of Graz, Harrachgasse 21/III, A-8010 Graz, Austria.
作者：
关键词
ATF6ApoptosisCATCODHAERFCSGPXHOHO-1Heme oxygenaseHuman aortic smooth muscle cellIRE1aKeap1Kelch-like ECH-associated proteinNrf2PERKRFUROSUPRX-box binding protein 1XBP-1activating transcription factor 6carbon monoxidecatalasedocosahexaenoic acideIF-2aendoplasmatic reticulumeukaryotic initiation factor 2 alphafetal calf serumglutathione peroxidasehASMChPASMChuman pulmonary artery smooth muscle cellsinositol-requiring enzyme 1alphan-3 PUFAn-3 polyunsaturated fatty acidnuclear factor erythroid 2-related factor-2protein kinase RNA-like endoplasmic reticulum kinasereactive oxygen speciesrelative fluorescent unitsunfolded protein response
主题词
抗氧化剂(Antioxidants);细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);环氮氧化物(Cyclic N-Oxides);DNA结合蛋白质类(DNA-Binding Proteins);二十二碳六烯酸类(Docosahexaenoic Acids);剂量效应关系, 药物(Dose-Response Relationship, Drug);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);基因沉默(Gene Silencing);血红素加氧酶-1(Heme Oxygenase-1);人类(Humans);肌, 平滑, 血管(Muscle, Smooth, Vascular);NF-E2相关因子2(NF-E2-Related Factor 2);氧化性应激(Oxidative Stress);肺动脉(Pulmonary Artery);RNA, 小分子干扰(RNA, Small Interfering);活性氧(Reactive Oxygen Species);自旋标记物(Spin Labels);时间因素(Time Factors);转录因子(Transcription Factors);非折叠蛋白质应答(Unfolded Protein Response)
DOI
10.1016/j.atherosclerosis.2013.08.002
PMID
24075775
发布时间
2016-11-25
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Atherosclerosis
406-13页
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