换一批Antiparasitic effect of a fraction enriched in tight-binding protease inhibitors isolated from the Caribbean coral Plexaura homomalla.
第一作者：
Emir,Salas-Sarduy
第一单位：
Centro de Estudio de Proteínas, Facultad de Biología, Universidad de la Habana, 25 #455 Entre J e I, La Habana, Cuba; Red CYTED-PROMAL (210RT0398), Proteómica y Quimiogenómica de Inhibidores de Proteasas de Origen Natural con Potencial Terapéutico en Malaria, Universidad Nacional de la Plata, La Plata, Argentina. Electronic address: emirsalas@gmail.com.
作者：
关键词
7-amino-4-methyl coumarinAAFPACNAMCAUAntiparasitic agentsBAPACMDCysteine peptidasesE-64IFN-(4-metoxiphenylazoformyl)-L-phenylalanineNaAcPlasmodium falciparumPlexaura homomallaRPRTTFATight-binding inhibitorTrypanosoma cruziZ-FR-AMCabsorbance unitsacetonitrilebenzoyl-arginyl-p-nitro-anilide-HClbenzyloxycarbonyl-Phenyl-Arginyl-7-amino-4-methyl coumarincarboxymethyl dextranintensity fadingreverse-phaseroom temperaturesodium acetate buffertrans-epoxysuccinyl-l-leucylamido-(4-guanidino)butanetrifluoracetic acid
医学主题词
动物(Animals);珊瑚虫纲(Anthozoa);抗原虫药(Antiprotozoal Agents);牛(Cattle);半胱氨酸内肽酶类(Cysteine Endopeptidases);半胱氨酸蛋白酶抑制剂(Cysteine Proteinase Inhibitors);剂量效应关系, 药物(Dose-Response Relationship, Drug);红细胞(Erythrocytes);人类(Humans);半数抑制浓度(Inhibitory Concentration 50);木瓜蛋白酶(Papain);恶性疟原虫(Plasmodium falciparum);原虫蛋白质类(Protozoan Proteins);光谱法, 质量, 基质辅助激光解吸电离(Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization);猪(Swine);克鲁斯锥虫(Trypanosoma cruzi);Vero细胞(Vero Cells)
DOI
10.1016/j.exppara.2013.09.013
PMID
24090569
发布时间
2022-03-21
- 浏览61
Experimental parasitology
611-22页
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