Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response.

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第一作者： Sudhakar,Deeti

第一单位： UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address: sudhakar.deeti@ucdconnect.ie.

作者： Sudhakar,Deeti ^[1] ; Sean,O'Farrell ^[2] ; Breandán N,Kennedy ^[3]

作者单位： UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address: sudhakar.deeti@ucdconnect.ie. ^[1] UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address: sean.o'farrell@kcl.ac.uk. ^[2] UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address: brendan.kennedy@ucd.ie. ^[3]

关键词 Drug treatment ERG OKR OMR Ocular toxicity VMR Visual behaviour assays Visual function Visualmotor response Zebrafish days post fertilisation dpf electroretinogram hours post fertilisation hpf optokinetic response optomotor response visualmotor response

主题词动物(Animals);药物评价, 临床前(Drug Evaluation, Preclinical);人类(Humans);幼虫(Larva);运动活动(Motor Activity);眼震, 视动性(Nystagmus, Optokinetic);视网膜(Retina);视觉, 眼(Vision, Ocular);斑马鱼(Zebrafish)

DOI 10.1016/j.vascn.2013.09.002

PMID 24091134

发布时间 2022-03-18

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Journal of pharmacological and toxicological methods

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Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response.

Journal of pharmacological and toxicological methods

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Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response.

Journal of pharmacological and toxicological methods

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Journal of pharmacological and toxicological methods

相关期刊

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