Heme oxygenase-1 exerts a protective role in ovalbumin-induced neutrophilic airway inflammation by inhibiting Th17 cell-mediated immune response.
作者:
主题词
动物(Animals);哮喘(Asthma);疾病模型, 动物(Disease Models, Animal);基因表达调控(Gene Expression Regulation);血红素加氧酶-1(Heme Oxygenase-1);氯化血红素(Hemin);人类(Humans);免疫, 先天(Immunity, Innate);炎症(Inflammation);白细胞介素17(Interleukin-17);肺(Lung);金属卟啉类(Metalloporphyrins);小鼠(Mice);中性白细胞(Neutrophils);核受体亚家族1, F组, 成员3(Nuclear Receptor Subfamily 1, Group F, Member 3);原卟啉类(Protoporphyrins);RNA, 小分子干扰(RNA, Small Interfering);STAT3转录因子(STAT3 Transcription Factor);Th17细胞(Th17 Cells)
DOI
10.1074/jbc.M113.494369
PMID
24097973
发布时间
2022-04-08
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