换一批A thioredoxin reductase and/or thioredoxin system-based mechanism for antioxidant effects of ambroxol.
第一作者：
Jin,Huang
第一单位：
College of Life Sciences, University of Chinese Academy of Sciences, YuQuan Road 19(A), 100049 Beijing, China.
作者：
关键词
2′,7′-dichlorofluorescin2′-7′-dichlorodihydrofluorescein diacetate3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide5,5′-dithiobis-(2-nitrobenzoic acid)5-(iodoacetamido)fluorescein5-IAFABXAmbroxolDCFDCFH-DADTNBDTTGua HClMTTPMSFROSReactive oxidative speciesThioredoxinThioredoxin reductaseTrxTrxRdithiothreitolguanidine hydrochloridephenylmethanesulfonyl fluorideradical oxidative speciesthioredoxinthioredoxin reductasetrans-4-(2-amino-3,5-dibromobenzylamino)-cyclohexanol, ambroxol
医学主题词
氨溴索(Ambroxol);动物(Animals);抗氧化剂(Antioxidants);支气管(Bronchi);牛(Cattle);细胞系(Cell Line);细胞存活(Cell Survival);剂量效应关系, 药物(Dose-Response Relationship, Drug);上皮细胞(Epithelial Cells);人类(Humans);过氧化氢(Hydrogen Peroxide);氧化性应激(Oxidative Stress);蛋白质结合(Protein Binding);RNA, 小分子干扰(RNA, Small Interfering);活性氧(Reactive Oxygen Species);硫氧还蛋白二硫化物还原酶(Thioredoxin-Disulfide Reductase);硫氧还蛋白质类(Thioredoxins)
DOI
10.1016/j.biochi.2013.09.024
PMID
24103200
发布时间
2014-01-13
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