Identification of single nucleotide polymorphisms in hematopoietic cell transplant patients affecting early recognition of, and response to, endotoxin.

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第一作者： Eva C,Guinan

第一单位： Boston Children's Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA Dana-Farber Cancer Institute, Boston, MA, USA.

作者： Eva C,Guinan ^[1] ; Christine D,Palmer ^[2] ; Christy J,Mancuso ^[3] ; Lisa,Brennan ^[4] ; Liat,Stoler-Barak ^[3] ; Leslie A,Kalish ^[5] ; Eugenie E,Suter ^[3] ; Leighanne C,Gallington ^[3] ; David P,Huhtelin ^[6] ; Maria,Mansilla ^[7] ; Ralf R,Schumann ^[8] ; Jeffrey C,Murray ^[7] ; Jerrold,Weiss ^[6] ; Ofer,Levy ^[9]

作者单位： Boston Children's Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA Dana-Farber Cancer Institute, Boston, MA, USA. ^[1] Boston Children's Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Boston, MA, USA. ^[2] Boston Children's Hospital, Boston, MA, USA. ^[3] Dana-Farber Cancer Institute, Boston, MA, USA. ^[4] Boston Children's Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA. ^[5] University of Iowa and Veterans' Administration Medical Center, Coralville, Iowa City, IA, USA. ^[6] Department of Pediatrics, University of Iowa, IA, Iowa City, USA. ^[7] Institute for Microbiology, Charité-University Medical Center, Berlin, Germany. ^[8] Boston Children's Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA ofer.levy@childrens.harvard.edu. ^[9]

关键词 CD14 LPS-binding protein (LBP)TNF bactericidal/permeability-increasing protein (BPI)bone marrow transplant hematopoietic cell transplant (HCT)lipopolysaccharide (LPS)