Autocrine VEGF signaling promotes proliferation of neoplastic Barrett's epithelial cells through a PLC-dependent pathway.
第一作者:
Qiuyang,Zhang
第一单位:
Center for Esophageal Diseases, VA North Texas Health Care System and the University of Texas Southwestern Medical School, Dallas, Texas; Department of Internal Medicine, VA North Texas Health Care System and the University of Texas Southwestern Medical School, Dallas, Texas.
作者:
关键词
ApoptosisBAR-TBrdUERKEsophageal CancerMouse ModelPKCPLCPLCG1VEGFVEGF-NAVEGFRVascular Endothelial Growth Factor Receptor 2bromodeoxyuridineextracellular signal-regulated kinasemRNAmessenger RNAnon-neoplastic, telomerase-immortalized Barrett's epithelial cellphospholipase Cphospholipase Cγ1protein kinase Crecombinant human vascular endothelial growth factorrhVEGFshRNAshort-hairpin RNAsiRNAsmall interfering RNAvascular endothelial growth factorvascular endothelial growth factor neutralization antibodyvascular endothelial growth factor receptor
主题词
腺癌(Adenocarcinoma);动物(Animals);抗肿瘤药(Antineoplastic Agents);自身分泌性细胞间通讯(Autocrine Communication);Barrett食管(Barrett Esophagus);细胞系(Cell Line);细胞增殖(Cell Proliferation);食管肿瘤(Esophageal Neoplasms);女(雌)性(Female);人类(Humans);免疫组织化学(Immunohistochemistry);吲哚类(Indoles);MAP激酶信号系统(MAP Kinase Signaling System);小鼠(Mice);磷脂酶Cγ(Phospholipase C gamma);磷酰化(Phosphorylation);癌前状态(Precancerous Conditions);蛋白激酶C(Protein Kinase C);吡咯类(Pyrroles);治疗结果(Treatment Outcome);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管内皮生长因子受体2(Vascular Endothelial Growth Factor Receptor-2)
DOI
10.1053/j.gastro.2013.10.011
PMID
24120473
发布时间
2024-06-10
- 浏览22

Gastroenterology
461-72.e6页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文