Targeting tumor micro-environment for design and development of novel anti-angiogenic agents arresting tumor growth.
第一作者:
Rajesh N,Gacche
第一单位:
School of Life Sciences, Swami Ramanand Teerth Marathwada University, Vishnupuri, Nanded 431606, India. Electronic address: rngacche@rediffmail.com.
作者:
关键词
1,3,6-Naphthalenetrisulfonate55?kDa protein75?kDa proteinALAAMAM binding protein-1AMBP-1ATPAngAngiogenesisAngiogenic cytokines/peptidesAngiopoietin-1Angp-1Angp-2Antiangiogenic agentsCDRsCGRPCLRCMLCXC receptor1CXC receptor2CXC receptor4CXCR1CXCR2CXCR4DHLAECEGFEGFRFGFFIHFactor-inhibiting hypoxia-inducible factorG protein coupled receptorsGPCRHGFHIF-1IGFIGF-1RIGF-2RIGF-binding proteinsIGFBPsIL-1IL-3IL-6IL-6rIL1RIRJAKsMCPMIPNGFNTSNeuropilin1Neuropilin2Nrp 2Nrp1PAMPPDBPGDFPGDFRPGFPGFRPHDsRAMPRNase-ASCFSDF-1alphaSDF-1αTGF-αTGF-βTNF-receptorTNF-αTNFRTie2KTumor necrosis factor-alphaVEGFVEGF ReceptorVEGF homology domainVEGFRVHDadenosine triphosphatealpha linolenic acidandrenomedullinangiogeninangiopoietin-2calcitonin gene-related peptidecalcitonin receptor-like receptorchronic myelogenous leukemiacomplementarity-determining regionscytoplasmic kinase domain of Tie2dihomo gamma-linolenic acidendothelial cellsepidermal growth factorepidermal growth factor receptorfibroblast growth factorhepatocyte growth factorhypoxia inducible factor-1insulin receptorsinsulin-like growth factorinsulin-like growth factor receptor type1insulin-like growth factor receptor type2interleukin 6interleukin 6 receptorinterleukin-1interleukin-3janus kinasesmacrophage inflammatory proteinmonocyte chemotactic proteinnerve growth factorp55p75placenta growth factorplacenta growth factor receptorplatelet derived growth factorplatelet derived growth factor receptorproadrenomedullin N-terminal 20 peptideprolyl hydroxylasesprotein data bankreceptor activity modifying proteinribonuclease-Astem-cell factorstromal cell-derived factor-1αtransforming growth factor-alphatransforming growth factor-betatype I IL-1 receptorvascular endothelial growth factor
主题词
血管生成抑制剂(Angiogenesis Inhibitors);血管生成蛋白质类(Angiogenic Proteins);动物(Animals);细胞增殖(Cell Proliferation);人类(Humans);模型, 生物学(Models, Biological);分子靶向治疗(Molecular Targeted Therapy);肿瘤(Neoplasms);新生血管化, 病理性(Neovascularization, Pathologic);肿瘤微环境(Tumor Microenvironment)
DOI
10.1016/j.pbiomolbio.2013.10.001
PMID
24139944
发布时间
2013-11-15
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