Activation of cyclic AMP/PKA pathway inhibits bladder cancer cell invasion by targeting MAP4-dependent microtubule dynamics.-论文-万方医学网

作者： Yanqiu,Ou ^[1] ; Xiaoke,Zheng ^[2] ; Yixing,Gao ^[3] ; Minfeng,Shu ^[4] ; Tiandong,Leng ^[4] ; Yan,Li ^[4] ; Wei,Yin ^[5] ; Wenbo,Zhu ^[4] ; Yijun,Huang ^[4] ; Yuxi,Zhou ^[4] ; Jianjun,Tang ^[4] ; Pengxin,Qiu ^[4] ; Guangmei,Yan ^[4] ; Jun,Hu ^[6] ; Huaizhen,Ruan ^[7] ; Haiyan,Hu ^[8]

作者单位： Department of Pharmacology, Zhong-shan Medical College, Sun Yat-Sen University, Guangzhou, P.R. China; Guangdong Provincial Cardiovascular Institute, Guangdong General Hospital, Guangdong Provincial Academy of Medical Sciences, Guangzhou, P.R. China. ^[1] Department of Phathology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, P.R. China; Department of Pharmacology, Zhong-shan Medical College, Sun Yat-Sen University, Guangzhou, P.R. China. ^[2] Department of Neurobiology, College of Basic Medical Science, The Third Military Medical University, Chongqing, P.R. China. ^[3] Department of Pharmacology, Zhong-shan Medical College, Sun Yat-Sen University, Guangzhou, P.R. China. ^[4] Department of Biochemistry, Zhong-shan Medical College, Sun Yat-Sen University, Guangzhou, P.R. China. ^[5] Department of Microbiology, Zhong-shan School of Medcine, Sun Yat-Sen University, Guangzhou, P.R. China; Department of Pharmacology, Zhong-shan Medical College, Sun Yat-Sen University, Guangzhou, P.R. China. Electronic address: hujun@mail.sysu.edu.cn. ^[6] Department of Neurobiology, College of Basic Medical Science, The Third Military Medical University, Chongqing, P.R. China. Electronic address: Ruanhzruan61@yahoo.com. ^[7] Department of Pharmaceutics, School of Pharmaceutical Science, Sun Yat-Sen University, Guangzhou, P.R. China. Electronic address: lsshhy@mail.sysu.edu.cn. ^[8]

主题词布拉地新(Bucladesine);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞存活(Cell Survival);霍乱毒素(Cholera Toxin);环AMP(Cyclic AMP);环AMP依赖性蛋白激酶催化亚单位(Cyclic AMP-Dependent Protein Kinase Catalytic Subunits);细胞骨架(Cytoskeleton);人类(Humans);免疫印迹法(Immunoblotting);免疫组织化学(Immunohistochemistry);显微镜检查, 共焦(Microscopy, Confocal);微管相关蛋白质类(Microtubule-Associated Proteins);微管(Microtubules);肿瘤侵润(Neoplasm Invasiveness);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);RNA干扰(RNA Interference);信号传导(Signal Transduction);微管蛋白(Tubulin);膀胱肿瘤(Urinary Bladder Neoplasms)

DOI 10.1016/j.urolonc.2013.06.017

PMID 24140250

发布时间 2022-12-07

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Activation of cyclic AMP/PKA pathway inhibits bladder cancer cell invasion by targeting MAP4-dependent microtubule dynamics.

Urologic oncology

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Urologic oncology

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Activation of cyclic AMP/PKA pathway inhibits bladder cancer cell invasion by targeting MAP4-dependent microtubule dynamics.

Urologic oncology

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Urologic oncology

相关期刊

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